Salman Azhar, Ph.D.

Salman Azhar, Ph.D.

Dr. Azhar serves as Associate Director for Research at the VA Palo Alto Geriatric Research Education and Clinical Center (GRECC); and Consulting Professor of Gastroenterology and Hepatology, Stanford University.  Dr. Azhar earned a Master of Science in Biochemistry at the University of Lucknow, U.P., India in 1968, and his Ph.D. in Chemistry at the Kanpur University, Kanpur, U.P, India in 1973.  He completed his postdoctoral work in reproductive endocrinology at the University of Michigan, Ann Arbor, MI in 1976. His main research interest include:

  • Underlying mechanisms by which HDL-cholesterol or “good cholesterol” acts as a scavenger, carrying LDL-cholesterol or “bad cholesterol” away from the arteries and back to the liver where it is broken down and passed from the body or to steroid producing tissues for product formation or storage.
  • Pre-clinical efficacy of a creosote bush-derived (plant) compound, called nordihydroguaiaretic acid (NDGA) against Metabolic Syndrome (MetS), the umbrella description given to a number of derangements associated with obesity and overweight.
  • Role of oxidative stress (oxidative stress, defined as a disturbance in the balance between the production of reactive oxygen species (free radicals) and antioxidant defenses, in age-related decline in steroid hormone production using various rodent models of aging and oxidative stress. Age-related decline in steroid production is a significant health problem in humans.