Jeremy Sokolove, M.D.
Dr. Sokolove is a Physician Scientist at the VA Palo Alto Health Care System with a focus on translational immunology. He has an academic appointment as Clinical Assistant Professor of Medicine at Stanford University. He earned his MD from Boston University School of Medicine where he was elected to Alpha Omega Alpha and completed his residency in Internal Medicine at Boston University Medical Center where he was selected as Chief Medical Resident. After serving for three years as a General Medical Officer and Staff Internist in the US Navy including Deployment with the Marine 3rd Force Service Support Group, Dr. Sokolove completed a two-year clinical fellowship in Rheumatology at Stanford University followed by a postdoctoral fellowship with Dr. William H. Robinson also at Stanford. In 2011, Dr. Sokolove received a VA Career Development Award (Level 2) and joined the staff at the VA Palo Alto. In addition, Dr. Sokolove serves as a PAVIR Principal Investigator.
Dr. Sokolove’s research group studies the initiation, propagation, and effector phases of chronic inflammation with a focus on rheumatoid arthritis (RA), osteoarthritis, and atherosclerosis. Much of this work has studied the intersection between innate and adaptive immunity including the seminal observation that a post-translational modification known as citrullination not only renders many proteins autoantigenic in rheumatoid arthritis, but additionally imparts robust innate immunostimulatory capacity via the Toll-like receptor family of receptors. Work continues to explore the role of protein citrullination in the pathophysiology of a variety of inflammatory conditions. In addition, the Sokolove group continues work in collaboration with the Robinson lab to identify and deploy robust biomarkers to study the pre-clinical evolution of RA as well as subphenotyping RA disease pathology. The overarching goal of the Sokolove group is to identify pathways critical to chronic inflammation which may prove amenable to therapeutic intervention.